http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103709146-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4709 |
| filingDate | 2014-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103709146-B |
| titleOfInvention | One class is containing the quinolin-4-amines derivative of benzimidazole structure, its method for making and medicinal use |
| abstract | One class, containing the quinolin-4-amines derivative of benzimidazole structure, is characterized in that it has following general formula:n r in formulan 1 representative: hydrogen, methyl, methoxyl group, hydroxyl, chlorine, fluorine, trifluoromethyl; Rn 2 representative: hydrogen, methyl, fluorine, chlorine, bromine, trifluoromethyl; Rn 3 representative: hydrogen, methyl, ethyl, fluorine, chlorine, bromine, trifluoromethyl; Rn 4 representative: hydrogen, fluorine, chlorine; Rn 5 representative: hydrogen, chlorine; Result of study shows, quinolin-4-amines Derivatives In Mice melanoma cell (F10) containing benzimidazole structure of the present invention, human cervical carcinoma cell (Hela), human liver cancer cell (HepG2) and human breast cancer cell (MCF7) have significant restraining effect, and therefore the quinolin-4-amines derivative containing benzimidazole structure of the present invention can be applied to and prepare anti-tumor drug.The invention discloses its method for making. |
| priorityDate | 2014-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 135.