http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103665054-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H3-04 |
| filingDate | 2013-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103665054-B |
| titleOfInvention | The preparation method of neolactose |
| abstract | The invention discloses a kind of preparation method of neolactose.The inventive method starting raw material used is 1,2-O-(1-methyl ethylidene)-3-O-ethanoyl-α-D-glucofuranose, glycosyl acceptor 1 is obtained by reacting by 3 steps, 2-O-(1-methyl ethylidene)-3-O-ethanoyl-5-O-benzoyl-α-D-glucofuranose intermediate, often walking the yield of reaction and purity, all very high (yield is respectively 97%, 100%, 95%, purity is respectively 99.5%, 99.2%, 99.8%), therefore, during a large amount of preparation, intermediate IV and V does not need purifying can be directly used in next step reaction; The present invention obtains Formula VII by intermediate formula VI and formula III coupling, by the reaction conditions of the above-mentioned explanation of preferred gained, productive rate high (80%), stereoselectivity good (can't detect isomer), be easy to purifying, the above-mentioned total recovery preparing disaccharide formula VII by four-step reaction by Formula II is 74%, and purity is 99.8%; (3) purity of final product of the present invention is high, and purity is not less than 98%. |
| priorityDate | 2013-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 208.