| abstract |
The invention relates to a tenofovir prodrug and its application in medicine. Specifically, the present invention relates to a compound represented by general formula (I) or its isomer, pharmaceutically acceptable salt, hydrate or solvate, and their use in the preparation and treatment of viral infectious diseases, especially AIDS (HIV ) infection, hepatitis B and diseases caused by hepatitis B virus, wherein the definition of each substituent in the general formula (I) is the same as that in the description. |