http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103664900-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-06 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C63-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-06 |
filingDate | 2013-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103664900-B |
titleOfInvention | A kind of method preparing rizatriptan benzoate |
abstract | The invention discloses a kind of preparation method of new rizatriptan benzoate.This preparation method is starting raw material with tryptamines, methylates through N, N, reduction, upper protection, triazole methylate, deprotection, dehydrogenation, salify seven step react, obtain highly purified rizatriptan benzoate.The innovation of the method is that have employed a kind of brand-new method builds indole ring, avoids the fisher indole synthesis used in existing route and the product foreign matter content brought is high, is difficult to the shortcoming of purifying.The advantage of the method is: easy and simple to handle, and reaction conditions is gentle, and without expensive reagent, do not need column chromatography purification, product purity is high. |
priorityDate | 2013-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 98.