| abstract |
The invention relates to a heteroaryl-substituted dihydropyrimidine compound and its use as medicine, especially the medicine for treating and preventing hepatitis B. Specifically, the present invention relates to compounds represented by general formula (I) or (Ia) or their enantiomers, diastereoisomers, hydrates, solvates or pharmaceutically acceptable salts, wherein Each variable is as defined in the specification. The present invention also relates to compounds represented by general formula (I) or (Ia) or their enantiomers, diastereomers, hydrates, solvates or pharmaceutically acceptable salts or pharmaceutical compositions thereof purposes, especially as a medicine for the treatment and prevention of hepatitis B. |