abstract |
The invention discloses a 2,3,4,6-tetrasubstituted phenol derivative, the structure of which is shown in formula (I). The invention also discloses a preparation method of 2,3,4,6-tetrasubstituted phenol derivatives. Under room temperature and nitrogen protection, enyne ether compounds and 1,3-dicarbonyl compounds are used as raw materials, and iron The salt is used as a catalyst, and the 2,3,4,6-tetrasubstituted phenol derivatives are synthesized in the presence of a base. The preparation method of the invention has beneficial effects such as low cost, mild reaction conditions, and environmental friendliness. |