http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103656742-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8b2e4f17c10a288dc28521ed1e17a0d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44ae178fe5ea1fd193b8e5e1baf1ab3b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-728 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/D04H1-4382 |
| filingDate | 2013-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81df5c8db831e15fd20c0a951b40a465 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f14584cfcfffe5987003d60c03b6f997 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b138b071547942506289aa7cce36de36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fe3d6de61fdcfea03ac817ba55af469 |
| publicationDate | 2015-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103656742-B |
| titleOfInvention | Preparation method of functionalized retinal pigment epithelial cell graft |
| abstract | The invention provides a preparation method of a functionalized retinal pigment epithelial cell graft. The preparation method comprises the following steps: taking a nano bionic Bruch's membrane as a retinal pigment epithelial cell carrier, inoculating retinal pigment epithelial cells onto the nano bionic Bruch's membrane, and performing co-culture under low-serum and low-sugar culture conditions to obtain the functionalized retinal pigment epithelial cell graft, wherein the nano bionic Bruch's membrane is an ultrathin porous antheraea pernyi silk fibroin/polycaprolactone/gelatin compound nanofiber membrane prepared by dissolving the antheraea pernyi silk fibroin, polycaprolactone and the gelatin in an organic solvent to form an electrostatic spinning solution and performing electrostatic spinning on the electrostatic spinning solution by an electrostatic spinning method. The functionalized retinal pigment epithelial (RPE) cell graft prepared by the method is capable of effectively avoiding the problems of high possibility of the RPE cells, cell polarity disorder and the like after transplantation in a conventional method, and can be widely applied to cell transplantation. |
| priorityDate | 2013-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 57.