http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103656694-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_140efb7e2a330be53d94bda6ad75cbe5 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-06 |
| filingDate | 2013-12-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b92082407729131961dfa3905b1d5cd |
| publicationDate | 2015-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103656694-B |
| titleOfInvention | 18F-labelled quinazolines irreversible EGFR (epidermal growth factor receptor) positive electron tracer agent, as well as preparation method and application thereof |
| abstract | The invention discloses an <18>F-labelled quinazolines irreversible EGFR (epidermal growth factor receptor) positive electron tracer agent, as well as a preparation method and application thereof. The <18>F-labelled quinazolines irreversible EGFR positive electron tracer agent has a chemical structure represented by the formula II. The synthesized 18F-labelled small-molecular irreversible EGFR positive electron tracer agent has a clinical value for diagnosing and monitoring a treating effect and particularly plays an important role in pushing individual-based treatment. Furthermore, the invention further provides a one-step method for synthesizing the <18>F-labelled small-molecular irreversible EGFR positive electron tracer agent. The method has the characteristics of multiple purposes, high yield, high efficiency, short synthesis time, low cost and the like and can meet a requirement on large-scale production. |
| priorityDate | 2013-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.