http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103642759-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-215 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 |
| filingDate | 2013-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103642759-B |
| titleOfInvention | The restructuring infectious bronchitis virus of chimeric IBV 4/91 strain spike protein film outskirt gene fragment and construction process thereof and application |
| abstract | Do you the invention discloses a kind of chimeric IBV? the restructuring infectious bronchitis virus of 4/91 strain spike protein film outskirt gene fragment and construction process thereof and application.Recombinant virus of the present invention builds by the following method to obtain: will adapt to the skeleton virus IBV of cell cultures? does is the spike protein film outskirt gene fragment of Beaudette strain replaced as IBV? the spike protein film outskirt gene fragment of 4/91 strain carrys out construction of recombinant virus, after virus rescue process on Vero cell blind passage 3-5 generation, do you until specific cells pathology-synplasm phenomenon occurs, namely obtain chimeric IBV? the restructuring infectious bronchitis virus of 4/91 strain spike protein film outskirt gene fragment.The present invention is built obtain restructuring infectious bronchitis virus inoculation chicken after show, recombinant virus of the present invention not only all safe to various chicken, without side reaction, and can challenge inoculation chicken produce opposing wild type strains 49/1 attack immunizing power. |
| priorityDate | 2013-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 152.