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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-04
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18
filingDate 2013-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103641846-B
titleOfInvention The preparation method of the amino rocephin of 7-
abstract The invention belongs to field of medicaments, be specifically related to the preparation method of the amino rocephin of a kind of 7-.Be suspended in methylcarbonate by 7-amino-cephalosporanic acid, triazine ring and EDTA, add boric carbonic acid dimethyl ester complex trifluoride, reaction, aftertreatment obtains the amino rocephin of 7-.7-ACA and triazine ring is adopted to use green economy solvent methylcarbonate as solvent, boric carbonic acid dimethyl ester complex trifluoride is the amino rocephin of catalyzer synthesis 7-, adopt nontoxic, environmental-protecting performance is excellent, price is low relative to acetonitrile, have aborning safe and convenient to use, pollute less, the methylcarbonate of the easy feature such as transport is as solvent, avoid the use of the noxious solvents such as volatile acetonitrile, make the relative environmental protection of reaction process, the security of operation improves.The relative acetonitrile of price of methylcarbonate is cheap, greatly reduces production cost, and the method adopts low cost and the starting material of environmental protection, and building-up process is simple, and yield is higher.
priorityDate 2013-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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