http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103638533-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-08 |
| filingDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103638533-B |
| titleOfInvention | A kind of preparation method of the hypotoxic magnetic Nano rod of targeting HIF |
| abstract | The preparation method of the hypotoxic magnetic Nano rod of the present invention a kind of targeting HIF, belongs to targets neoplastic cells treatment magnetic Nano. At amino functional magnetic Nano ion (Fe 3 O 4 ) finishing bromination 4-acetylpyridine-2 ethyl bromide (ILs) obtains positively charged magnetic Nano ion (Fe 3 O 4 -ILs), then this nanoparticle is by the Electrostatic Absorption recognition sequence in conjunction with HIF, and this magnetic nanoparticle is sized to 8nm. Cytotoxicity experiment shows that this nanometer rods is a kind of hypotoxic nano material. Nuclear magnetic resonance experiment display nanometer rods energy significant difference tumor hepatocyte and normal liver cell, our invention is that the targeting magnetic nano-carrier building the induction of new series nucleic acid is laid a good foundation.<b /> |
| priorityDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.