http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103638528-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N15-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-04 |
| filingDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103638528-B |
| titleOfInvention | A nanoparticle for folate-targeted, its purposes and synthesis and detection method |
| abstract | The present invention relates to a kind of nanoparticle of folate-targeted, its purposes and synthesis and detection method.After antitumor drug administration, in non-specific distribution in body, toxic and side effects is large, and therapeutic index is low.Pharmaceutical carrier-the nanoparticle with active targeting function adopting nanotechnology to build, can effectively address this problem.Folic acid is conventional targeted molecular, and bootable medicine active targeting, containing the tumor cell of folacin receptor, improves drugs against tumor effect.The present invention selects plant sterol. and sodium alginate builds the Performances of Novel Nano-Porous grain of rice plant sterol-sodium alginate nanoparticles of folate-targeted, hydrophobic antitumor drug amycin bag is loaded in its hydrophobic inner core, be prepared into the nanoparticle of medicine carrying, make sodium alginate, new material that plant sterol becomes antineoplastic drug carrier, plant sterol-the sodium alginate nanoparticles of self assembly has safety, effectiveness and targeting as antineoplastic drug carrier, for it is applied to clinical providing fundamental basis as a kind of new drug carrier in the future. |
| priorityDate | 2013-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.