http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103638027-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 |
| filingDate | 2013-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103638027-B |
| titleOfInvention | Utilize method and the preparation of amphiphilic drug encapsulation hydrophobic anticancer drug |
| abstract | The invention discloses a kind of method utilizing amphiphilic drug encapsulation hydrophobic anticancer drug, comprising: amphiphilic medicine and hydrophobic anticancer drug join in organic solvent by (1), mix homogeneously; (2) add distilled water in the mixture obtained to step (1), mix homogeneously obtains formulation soln; (3) remove the organic solvent in formulation soln, add freeze drying protectant, lyophilization process, obtain wrapping the antineoplastic agent medicinal powder being loaded with hydrophobic anticancer drug.The present invention is the open pharmaceutical preparation prepared by said method also.The present invention adopts amphiphilic medicine irinotecan hydrochloride or topotecan hydrochloride to be emulsifying agent, bag carries the cancer therapy drug being insoluble in water, considerably increase dewatering medicament dissolubility in water, remain the high anti-tumor activity feature of medicine itself, and preparation technology is simple, the suitability is strong, facilitates large-scale production, for a new approach has been opened up in conveying in the body of hydrophobic drug. |
| priorityDate | 2013-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.