http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103623404-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-102 |
| filingDate | 2012-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103623404-B |
| titleOfInvention | A kind of preparation method of Type B hemophilus influenza polysaccharide conjugate vaccine |
| abstract | The invention discloses the preparation method of a kind of Type B hemophilus influenza polysaccharide conjugate vaccine, preparation method is: the polyoses extract of A.B type hemophilus influenza, PRP polysaccharide is dissolved to 20mg/ml with ultra-pure water or water for injection under room temperature, it is to add CDAP under conditions of 1 according to the mass ratio of PRP Yu CDAP, maintains 1.5min.0.3M NaOH regulates pH to 9.5, maintains 3min.It is the condition of 4:1 according to ADH Yu PRP polysaccharide mass ratio, adds solid ADH.0.3M NaOH regulates pH to 9.5, maintains 1h.28 DEG C, 0.2M NaCl dialyses；B. PRP AH and the 20mg/ml TT solution after dialysis mixes with mass ratio 1:2.0.1M HCL regulates pH to 5.0, then according to the ratio that EDAC Yu PRP mass ratio is 10:1 adds solid EDAC, maintains pH5.060min, 0.3M NaOH regulation pH to 7.5 to react 30min under room temperature. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/RU-2770877-C1 |
| priorityDate | 2012-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.