http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103613678-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2013-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103613678-B |
titleOfInvention | A kind of Sipunculus nudus polysaccharide sulfation modification method |
abstract | The invention discloses a kind of sulphation modification method of Sipunculus nudus polysaccharide.Sipunculus nudus polysaccharide has antibacterial, antiviral, the function such as radioprotective, enhancing body immunizing power.The activity of polysaccharide is subject to the impact of its molecular structure directly or indirectly, carries out suitably modifying the activity that can change polysaccharide, improve its effect to polysaccharide molecule structure.The present invention's chlorsulfonic acid-pyridine method carries out sulphation modification to Sipunculus nudus polysaccharide, by the purifying of Sipunculus nudus polysaccharide, the concrete technical measures such as the sulphation modification of Sipunculus nudus polysaccharide, obtain Sipunculus nudus controlling sulfate polyose, adopt disk diffusion method, with 6 kinds of bacteriums for indicator, Determination of Antibacterial Activity is carried out to Sipunculus nudus polysaccharide and optimum modification condition gained controlling sulfate polyose.Antibacterial tests result shows, and the Sipunculus nudus sulfating numerator modification product of the inventive method gained, can improve the anti-microbial activity of Sipunculus nudus polysaccharide further. |
priorityDate | 2013-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.