http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103613619-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H7-033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate | 2013-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103613619-B |
| titleOfInvention | The preparation method of N-4-benzene sulfonamido-N '-1-deoxidation-beta d glucopyranosiduronic acid base-thiourea compound and medicinal use |
| abstract | The invention discloses a class and there is suppression carbonic anhydrase n active so reach anti metastasis invasion and attack effect have general formula (n ) and (n ) shown in novel <i>N</iGreatT.Gr eaT.GT-4-benzene sulfonamido-<i>N</iGreatT.Gr the eaT.GT '-1-deoxidation-<i> β </i>-D-glucopyranosiduronic acid base-thiourea compound of structure.This compounds structurally has sulfanilamide (SN), replaces glucuronic acid and thiocarbamide three active fragmentss, can with carbonic anhydrasen in Znn 2+ ion and asparagicacid residue form coordinate bond and hydrogen bond respectively, realize the catalytic activity of inhibitory enzyme, play the effect of anti metastasis invasion and attack, as having potential application in antitumor drug.The general formula that the present invention relates to (n ) and (n ) in being defined in the specification of R, X and M. |
| priorityDate | 2013-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.