http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103613600-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-582 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-365 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-365 |
| filingDate | 2013-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-01-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103613600-B |
| titleOfInvention | Anilino-podophyllum derivative of tool anti-tumor activity and its production and use |
| abstract | The anilino-that the invention discloses tool anti-tumor activity replaces podophyllum derivative and its production and use.The present invention is reacted 4 chlorine 3 monomethylaniline .s by anilino-, 3 fluorine 4 aminoanisoles, 4, 4 ' MDAs, face aminoanisole, 4 chlorine 2 aminoanisoles, 2-Aminobenzonitrile, 2, 6 dichloro-4,4 amino-phenols, N, aniline between N dimethylamino, 2 ethyl 5 nitroanilines, 22 ' diamino diphenyl sulfide or 25 amido benzotrifluorides are introduced between podophyllotoxin or 4, the C ring of 4 ' demethyl epipodophyllotoxins activation, obtain the anilino-shown in formula (V) and replace podophyllum derivative, this derivant passes through multipath, multiple target effect is in tumor cell, its anti-tumor activity has had and has been obviously improved, antitumor drug can be prepared as and be applied to clinical antineoplastic treatment. |
| priorityDate | 2013-11-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.