| abstract |
The invention discloses a ragrazola analogue having an alkyl disulfide side chain as shown in formula 1, a preparation method thereof and an application thereof. The compound of the invention has higher antitumor activity and selectivity, It can be used to develop antitumor drugs, and the raw materials are cheap and easy to obtain, and the preparation method is simple, and it is a method suitable for industrialized production. Formula 1 wherein R is a C1-C8 alkyl group. |