http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103601695-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D263-26 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D263-26 |
| filingDate | 2013-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103601695-B |
| titleOfInvention | (S) preparation method of-4-benzyl-3-propionyl-2-oxazolidone |
| abstract | The invention belongs to organic synthesis and medicinal chemistry arts; relate to the synthetic method of a kind of pharmaceutical intermediate (S)-4-benzyl-3-propionyl-2-oxazolidone; take amino acid as raw material; carboxyl reduction is obtained aminophenylpropyl alcohol; again through cyclisation and addition reaction, obtain chiral intermediate molecule (S)-4-benzyl-3-propionyl-2-oxazolidone.Synthetic method design science of the present invention, execution path is succinctly reliable, is applicable to industrialization; Adopt microwave synthesis method in the committed step of reaction, yield is high, and required solvent is few, meets the development trend of Green Chemistry; Whole process yield is high, and each step is substantially all more than 90%, and total recovery is all more than 70%. |
| priorityDate | 2013-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 63.