Predicate |
Object |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5386 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5386 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 |
filingDate |
2013-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2016-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2016-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-103588792-B |
titleOfInvention |
Pyridopyrimidine or pyrimido-pyrimidine compounds, its preparation method, medical composition and its use |
abstract |
The invention belongs to medicinal chemistry art.Specifically, the present invention relates to a kind of following Pyridopyrimidine shown in general formula (I) or pyrimido-pyrimidine compounds or its isomer or its pharmacy acceptable salt, ester, prodrug or solvate, its preparation method, pharmaceutical composition and preparing the purposes in mTOR inhibitors.This compounds or its pharmaceutical composition can be used for treating the disease or illness that are caused by PI3K-AKT-mTOR signal path functional disorder as mTOR inhibitors. |
priorityDate |
2013-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |