| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ac31afbea1cbbb03498644721ffb4a62 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-12 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2013-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_408d65ac3f90dbfa5cc0ee5fe09f2730
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1be8c1052ef4aefc9bbd4b37ed740ec7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d69471d599bcc07ef2039c178ebdac90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aff9ecce90ad72fa12b16e4397bb5a28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8430571dd65611a3115674708737fd97 |
| publicationDate |
2014-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-103588758-A |
| titleOfInvention |
Synthesis, Preparation and Application of a Class of Nitroimidazole Derivatives Containing 1,4-Benzodioxane Skeleton in Anticancer Drugs |
| abstract |
A class of synthesis of nitroimidazole derivatives containing 1,4-benzodioxane skeleton is characterized in that it has the following general formula: The nitroimidazole derivative containing 1,4-benzodioxane skeleton of the present invention is effective to human lung adenocarcinoma cell line (A549), human cervical cancer cell line (HELA), human astrocytoma cell line ( U251) and human liver cancer cell line (HEPG2) have obvious inhibitory effect, so the imidazole derivatives of the present invention can be applied to the preparation of antitumor drugs. The invention discloses its preparation method. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017205622-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104402864-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104447712-A |
| priorityDate |
2013-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |