http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103588754-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d890ad239375a780e6827d3407f15ef3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-04 |
| filingDate | 2013-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_794f6500f520625867d9e517a170c326 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_75c2b864db3dc3294cf25df7e3d44b32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9814e8948c44f2aa0211f990d03d75f |
| publicationDate | 2015-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103588754-B |
| titleOfInvention | Preparation method of imatinib |
| abstract | The invention relates to a preparation method of imatinib (I). Specifically, after a 6-methyl-N-(4-(pyridin-3-yl)pyrimidin-2-yl)-1,3-phenylenediamine reaction substrate (II) or a salt thereof is subjected to a reaction with p-halogenated methylbenzoyl halide in an inert solvent and in the presence of an alkali, any separation and purification treatment of an intermediate are not required, an in situ reaction with 1-methyl piperazine is directly carried out, and then the imatinib (I) target compound is obtained. |
| priorityDate | 2013-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.