http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103588700-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_97a714fcb755e3262636236d7856f6b3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 |
| filingDate | 2013-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32762711ad0f901d18c6c17879bbf5d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_662f0dfbf18d4ee92413b7145874b6fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_182a61681f58cd4bad1ce78248704dc4 |
| publicationDate | 2015-04-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103588700-B |
| titleOfInvention | Method for resolving barnidipine mother nucleus by using glucosamine as resolving agent |
| abstract | The invention discloses a method for resolving a barnidipine mother nucleus by using glucosamine as a resolving agent. The method comprises the following process routes shown in the description: resolving the barnidipine mother nucleus by using the glucosamine as the resolving agent, wherein the easily available low-cost barnidipine is used as a chiral resolving agent for resolving the racemized barnidipine mother nucleus and solvents used in the middle are easily available and low-cost alcohol and water; and obtaining a single isomer of the barnidipine mother nucleus with high yield and high optical purity (ee value is 99.0-99.6%) with. The method has the beneficial effects that the resolving agent is low-cost and easily available, the using of expensive resolving agents is avoided, the used solvents are harmfulless, the resolution recovery rate is high, and the product has high optical purity and strong atom economy; the experiment operation is simple, reaction conditions are mild and easy to control, and the technology repeatability is high; and the implementation of the industrial production is easy. |
| priorityDate | 2013-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.