http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103585164-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-635 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 |
| filingDate | 2013-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103585164-B |
| titleOfInvention | Celecoxib solid composition that a kind of dissolution increases and its preparation method and application |
| abstract | The present invention relates to the medicine of a kind of osteoarthritis (OA) and adult rheumatoid arthritis (RA), relate in particular to Celecoxib solid composition of a kind of dissolution increase and its preparation method and application.Described Celecoxib solid composition is made up of celecoxib, dispersion enhancing agents and alkali compounds, and wherein the mass ratio of celecoxib, dispersion enhancing agents and alkali compounds is 100:5 ~ 95:0.1 ~ 1.5; The D90 of described Celecoxib solid composition is within the scope of 5 ~ 20 μm.No matter Celecoxib solid composition of the present invention solves celecoxib crude drug is monocrystalline type or under mixing polymorphous condition, material electrostatic is too large, the not easily technological difficulties of mixed powder, solve the hydrophilic of celecoxib, improve the physical characteristic of medicine indissoluble, add the dissolution of medicine, thus be conducive to the absorption of medicine. |
| priorityDate | 2013-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 86.