http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103571872-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-027 |
| filingDate | 2012-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103571872-B |
| titleOfInvention | A kind of preparation method of the transgenic animal that can express people's antibody |
| abstract | The present invention relates to produce the preparation method of the mice of people's antibody, the method includes the transgenic mice by carrying the Partial Fragment comprising human antibody heavy chain's locus, with carrying to be inserted in mouse gene group DNA, there is the mouse hybrid of the most rearranged human antibody light chain gene locus portion fragment, described human antibody heavy chain and light chain gene seat can carry out gene rearrangement and gene conversion in transgenic mice, to produce various people sources immunoglobulin.Wherein endogenous mouse antibody heavy chain gene seat, endogenous mouse antibody κ light chain gene seat and Lamda light chain gene seat are deactivated. |
| priorityDate | 2012-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.