http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103570701-B

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filingDate 2013-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103570701-B
titleOfInvention A kind of coumarin derivatives and its preparation method and application
abstract The invention provides a kind of coumarin derivatives and its preparation method and application, described coumarin derivatives, its molecular formula is Cn 13 hn 6 nn 2 on 4 .Its preparation method comprises: first prepare 4-chloromethyl-umbelliferone, 4-methylol-umbelliferone and umbelliferone-4-formaldehyde; Then umbelliferone-4-formaldehyde is added in water, then adds propane dinitrile and 1-Methylimidazole, stirring at room temperature, filter obtained 2,2-dicyano-3-(7-hydroxyl-skimmetine base) oxyethane.The present invention prepare 2,2-dicyano-3-(7-hydroxyl-skimmetine base) oxyethane can as the fluorescent probe of halfcystine in selective enumeration method organism, also can be used for halfcystine in fluorescence labeled cell, in clinical medicine, the diagnosis of relative disease is offered help.
priorityDate 2013-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 40.