http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103570689-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate | 2013-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-11-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103570689-B |
| titleOfInvention | For antitumor drug to nitro arylmethyl (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine anoxic activation prodrug |
| abstract | A kind of for antitumor drug to nitro arylmethyl (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine anoxic activation prodrug, its chemical name is: 5-(1-(1-(4-nitro arylmethyl) piperidin-4-yl)-1H-pyrazoles-4-base)-3-((R) the chloro-3-fluorophenyl of-1-(2,6-bis-) oxyethyl group) pyridine-2-amine; It utilizes nitro arylmethyl modifier, in the basic conditions, reacts with (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine, make it to nitro arylmethyl, obtained (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine anoxic activation prodrug---to nitro arylmethyl (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine.Its purposes is as principle active component for the preparation of anti-tumor agents, especially for the anti-tumor agents of preparation treatment hepatocellular carcinoma. |
| priorityDate | 2013-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 76.