| abstract |
The invention provides a 2-quinolinone compound and a preparation method and application thereof. The 2-quinolinone compound is 3-(2-benzimidazolyl)-6, 7-difluoro-2-quinolinone. The preparation method comprises the following steps: taking 3, 4-difluoro acetanilide as an initial raw material, reacting with POC13 (phosphorus oxychloride) and DMF (dimethyl formamide) to obtain 2-chlorine-6, 7-difluoro quinoline-3-formaldehyde, then hydrolyzing to generate 3-aldehyde group-6, 7-difluoro-2-quinolinone, then reacting with o-phenylenediamine to obtain the 2- quinolinone compound. The 2-quinolinone compound can be used as a fluorescent probe for quantitative detection of the content of Hg<2+>, and shows high sensitivity and selectivity, the detection process is simple and rapid, and the detection result is accurate. |