http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103570564-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-10 |
filingDate | 2013-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103570564-B |
titleOfInvention | A kind of Propafenone drug enantiomer method for splitting |
abstract | The invention provides a kind of Propafenone drug enantiomer method for splitting.The method with Propafenone hydrochloride for split object, first Propafenone hydrochloride is converted into Propafenone episome, with L-TARTARIC ACID ester class and boric acid as resolution reagent, L-TARTARIC ACID ester class is added in organic phase, boric acid adds in aqueous phase, adopts high-speed countercurrent chromatography to obtain left-handed Propafenone and dextrorotation Propafenone.Compared with prior art, beneficial effect of the present invention is mainly reflected in: adopt present method resolving chiral medicine Propafenone can reach higher resolution, and the method is applicable to the preparative counter current chromatograph of various model, can be separated the monomer obtaining left-handed Propafenone and dextrorotation Propafenone. |
priorityDate | 2013-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.