http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103566378-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-29 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2013-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103566378-B |
| titleOfInvention | Tumor nucleic acid vaccine based on tissue factor, preparation method and applications |
| abstract | The invention discloses a kind of tumor nucleic acid vaccine based on tissue factor, with plasmid as carrier, plasmid inserts the DNA sequence of coding HBc, and insert the DNA sequence of encoding human source TF target epitope polypeptide in the sequence, people source TF target epitope peptide sequence is shown in SEQ ID NO:1,74 94 amino acids of this polypeptide behaviour source TF；Containing ISS sequence in the noncoding region of described plasmid vector.Also disclose the preparation method and application of tumor nucleic acid vaccine.The present invention passes through genetic engineering means, using one section selected from TF comprise epi-position target sequence as epitope submission to the hepatitis B virus core antigen reconstructed on, build epitope nucleic acid vaccine, body is given by the method for intramuscular injection, host cell expression is promoted to go out the polypeptide containing TF target epitope, stimulate body to produce active immunity, thus obtain the preventive and therapeutic action to tumor. |
| priorityDate | 2013-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 56.