| abstract |
The present invention provides a nitrogen-containing saturated heterocyclic compound effective as a renin inhibitor drug. A compound or a pharmacologically acceptable salt thereof, wherein the compound is represented by formula I, In the formula, R 1 represents a cycloalkane group, etc., R 22 represents an aryl group that may be substituted, etc., R represents a lower alkane group, etc., T represents a carbonyl group, Z represents -O-, -NH-, etc., R 3 , R 4 , R 5 and R 6 are the same or different, and represent a hydrogen atom or the like. |