Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0059dbdf718b11e46352781ff874a5ef |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2547-101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2549-119 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6848 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2013-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2015-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_576284359c944f963d3959fc3a25a43c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1a408e0d7f1ea9d1a122a2e36b65df2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa60928586555bf3022fe71d9666b51c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06aa9bfc6d0c22f50f5cdbf0e2a0e338 |
publicationDate |
2015-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-103555827-B |
titleOfInvention |
Primers, method, and kit used for detecting BCR/ABL fusion gene ABL kinase domain drug resistance mutation sites |
abstract |
The invention discloses primers, a method, and a kit used for detecting ABL kinase domain drug resistance mutation sites in two shear-type M-bcr and m-bcr in BCR/ABL fusion gene. The kit comprises; (i) inner and outer primers used for amplifying M-bcr shear-type and m-bcr shear-type fusion gene ABL kinase domains; (ii) an antisense primer complementary with the outer primer; and (iii) a pair of sequencing primers covering all mutation hotspots in the BCR/ABL fusion gene ABL kinase domains. According to the invention, with a tube nested PCR technology, the kit and the method can be used for rapidly detecting the mutation of drug resistance sites in BCR/ABL fusion gene ABL kinase domains in chronic myelogenous leukemia patients. |
priorityDate |
2013-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |