| abstract |
The invention provides that MDCK derives, the new non-tumorigenic cells system of sticking together, growth under described clone can exist being with or without serum.Clone of the present invention can be used for producing vaccine materials (such as, virus).More particularly, clone of the present invention can be used for producing influenza virus, particularly ca/ts influenza virus usually.The present invention also provides and makes mdck cell adaptation and the method grown and substratum preparation thus make it maintain non-tumorigenic.In addition, the invention provides the method for producing vaccine materials (such as, influenza virus) with Novel cell lines of the present invention. |