http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103554527-B

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24
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filingDate 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23c1f6a245980c7964ca097be380fd25
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf413c43d22d0d455f1d7eec4d099808
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publicationDate 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103554527-B
titleOfInvention Collagen hydrogel capable of being reversed through hydrolysis and preparation method thereof
abstract The invention relates to a medical collagen hydrogel capable of being biologically reversed through hydrolysis, and a preparation method thereof. The hydrogel disclosed by the invention is mainly prepared from collagen and glycosaminoglycan in a cross-linking manner, wherein glycosaminoglycan is oxidized to form an aldehyde group to be mixed with the collagen; the aldehyde group in glycosaminoglycan and amino in the collagen are subjected to conjugate crosslinking reaction, so as to obtain the collagen hydrogel. The collagen hydrogel prepared by using the method disclosed by the invention has good hydrophilicity and biocompatibility; due to good flexibility, the collagen hydrogel can be tightly attached to the surface of a wound, so that new epithelial regeneration is facilitated, the wound healing time is shortened, and generation of a scar is reduced; the degradation rate can be regulated and controlled.
priorityDate 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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