http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103554527-B
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2485673898b49f6311688022257437bb |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-20 |
filingDate | 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23c1f6a245980c7964ca097be380fd25 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf413c43d22d0d455f1d7eec4d099808 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3c6e136b9aa2cb5ac5df575925c463f6 |
publicationDate | 2015-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103554527-B |
titleOfInvention | Collagen hydrogel capable of being reversed through hydrolysis and preparation method thereof |
abstract | The invention relates to a medical collagen hydrogel capable of being biologically reversed through hydrolysis, and a preparation method thereof. The hydrogel disclosed by the invention is mainly prepared from collagen and glycosaminoglycan in a cross-linking manner, wherein glycosaminoglycan is oxidized to form an aldehyde group to be mixed with the collagen; the aldehyde group in glycosaminoglycan and amino in the collagen are subjected to conjugate crosslinking reaction, so as to obtain the collagen hydrogel. The collagen hydrogel prepared by using the method disclosed by the invention has good hydrophilicity and biocompatibility; due to good flexibility, the collagen hydrogel can be tightly attached to the surface of a wound, so that new epithelial regeneration is facilitated, the wound healing time is shortened, and generation of a scar is reduced; the degradation rate can be regulated and controlled. |
priorityDate | 2013-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.