http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103554112-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0299e256f5589776d4bd724070719e5b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2013-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b2ef159a4671b94d6154bb3cd39abd4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fabb1cc8920d24d9c37c77826ff474b |
| publicationDate | 2014-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103554112-A |
| titleOfInvention | Synthetic method of cis-fused ring β-lactam compound |
| abstract | A synthetic method for a class of cis-fused ring β-lactam compounds shown in formula (I), using substituted or unsubstituted pyrrole-2-carboxylic acid, or substituted or unsubstituted pyridine-2-carboxylic acid, or substituted or Unsubstituted indole-2-carboxylic acid as the starting material, using Pd(II) as the catalyst, AgOAc or Ag 2 CO 3 as the oxidant, through palladium-catalyzed sp 3 CH on the β-position of the amide substrate 2 (such as Scheme4) The key step is the successful construction of the β-lactam skeleton of the cis-fused ring. The raw material of the present invention is simple and easy to obtain, low in price, simple in experimental operation, short in route, high in yield, high in atom economy, less in waste, good in environment, wide in scope of substrate application, good in universality and high in energy efficiency Optically active β-lactam compounds with chiral retention can be obtained. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109096168-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111087399-A |
| priorityDate | 2013-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.