http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103554037-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_71b7e531222e4be4285ee801c51feee2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-69 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-52 |
| filingDate | 2013-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f8625d2b2fb14b25983f3258c5dad41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dff9651769e7cc9baeab1614f2e391b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eea3396c1cd25e617e9bd7ddbd8b87e7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5505e419f93dc737faf5de3ed1eae8e0 |
| publicationDate | 2015-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103554037-B |
| titleOfInvention | Preparation method of bosentan metabolite (hydroxy bosentan) |
| abstract | The invention discloses a preparation method of a bosentan metabolite (hydroxy bosentan). Abundant screening experiments are performed to determine the optimal reactant consumption, reaction temperature, reaction time, reaction solvent and the like in the preparation technique; and the whole preparation technique has the advantages of high operability, high preparation efficiency and low production cost, and can implement industrialized mass production. The bosentan metabolite (hydroxy bosentan) prepared by the method has the advantages of higher bioavailability and lower untoward effect, and directly can have the antihypertensive effect. |
| priorityDate | 2013-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 293.