http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103553973-B
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a26bd1658772eb7d2a125c1cd8a6428b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C273-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C275-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-175 |
| filingDate | 2013-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76a20054e2e7d43a5ad5dac5b82be834 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2ee181bad7e9d0c1937d19ce0f2839c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b6922cafc9883be1ebb84ac95a92121 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e387086be532c6b65477254d5432d3cf |
| publicationDate | 2015-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103553973-B |
| titleOfInvention | o-nitroaroyl beta-chloroethyl nitrosourea compounds, preparation and use thereof |
| abstract | The present invention discloses o-nitroaroyl beta-chloroethyl nitrosourea compounds represented by a formula 1, a preparation method and a use thereof, wherein R is -COCH2C6H4NO2-o, or -COCH2CH2C6H4NO2-o, or -COCH2OC6H4NO2-o. According to the preparation method, o-nitro aromatic carboxylic acid is adopted as a synthesis raw material and is subjected to acylation, substitution, chlorination and nitrosation to obtain the target compound. The compounds can be used in preparation of tumor treatment drugs, particularly in preparation of breast cancer treatment drugs or glioblastoma treatment drugs or human cervical carcinoma treatment drugs or erythroleukemia treatment drugs. |
| priorityDate | 2013-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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