http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103539697-B

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filingDate 2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0559e98b9d7c0ae03c3c2f67ebfb595c
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publicationDate 2014-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103539697-B
titleOfInvention Synthesis of reduced sensitive azo connection unit and application of azo connection unit in DNA (deoxyribonucleic acid) sequencing
abstract The invention discloses synthesis of a reduced sensitive azo connection unit and application of the azo connection unit in DNA (deoxyribonucleic acid) sequencing. The reduced sensitive azo connection unit has the structural formula shown in the specification, wherein m is any integer of 0-44, and n is any integer of 0-44. The reduced sensitive azo connection unit is connected with nucleotides and fluorescein to obtain a reversible terminal, and the reversible terminal is used for DNA synthesis sequencing. Compared with the prior art, the reduced sensitive azo connection unit has the advantages that a type of novel cracking connection units are synthesized, and used for synthesizing a reversible terminal based on the connection unit; the reversible terminal can realize high-efficiency cracking under mild conditions and can be used for DNA synthesis sequencing; meanwhile, the raw materials required by synthesis are simple and readily available, the synthesis process is a conventional chemical reaction, and the reduced sensitive azo connection unit can be used for large-scale popularization and application.
priorityDate 2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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