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filingDate 2013-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2014-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_606a1d052327acee4cf8e7bb968ce780
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publicationDate 2014-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103524676-B
titleOfInvention Preparation method and application of monolithic 2-[(6-oxo-6H-benzo[c]chroman-3-yl)oxyl] propanoic acid column
abstract The invention discloses a preparation method and application of a monolithic 2-[(6-oxo-6H-benzo[c]chroman-3-yl)oxyl] propanoic acid column. An in-situ polymerization method is adopted, 2-[(6-oxo-6H-benzo[c]chroman-3-yl)oxyl] propanoic acid is used as a template molecule, 4-vinyl pyridine is used as a functional monomer, a methanol and distilled water mixed solution is used as a pore-forming agent, and a pre-polymerized solution is directly poured into a chromatographic column and is polymerized in a column pipe at one step, so that the complex column filling procedure is avoided, the preparation process is simple, and the preparation time is greatly shortened. The monolithic column obtained by using the method disclosed by the invention has specific selectivity for the template molecule, alternaria alternata toxin and structural analogues thereof, and is good in stability and capable of being used repeatedly; in addition, a substance to be detected is replaced with the cheap template molecule, so that the detection expense is reduced, the leakage problem of the template molecule is avoided, and the detection accuracy is improved.
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Total number of triples: 46.