http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103524564-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-555 |
| filingDate | 2013-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2015-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103524564-B |
| titleOfInvention | Platinum (II) the title complex synthetic method of the different aporphine of a kind of 6-amino group and application |
| abstract | Platinum (II) title complex that the invention discloses a kind of new different aporphine of the 6-amino group i.e. different aporphine of a Chlorodimethyl sulfoxide 6-amino group closes platinum (II), and its synthetic method and application.This title complex is that different for 6-amino group aporphine and dichloro two (dimethyl sulfoxide (DMSO)) are closed platinum (II), is dissolved in polar solvent, carries out heating or back flow reaction acquisition target product; Specifically by solution method synthesis, also by solvent structure.Applicant is by investigating it to the proliferation inhibition activity of the human tumor cell lines such as HepG2, BEL-7404 and NCI-H460, find that it has significant anti tumor activity in vitro to above-mentioned 3 kinds of tumor lines, there is good potential pharmaceutical use, be expected to the preparation for various antitumor drug.The chemical structural formula of above-mentioned title complex is shown below: |
| priorityDate | 2013-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.