abstract |
The invention belongs to the field of bactericide creation, and relates to a series of trichodermain C8 oxime ether derivatives with antibacterial activity against plant pathogenic fungi. Specifically, the invention discloses a trichodermain C8 oxime ether derivative, the general structural formula of the trichodermain C8 oxime ether derivative is: The invention also discloses its preparation method at the same time. In the invention, the oxime ether structure is used as an efficient molecular pharmacophore, and the functional group modification is carried out on the parent structure of trichoderma, thereby preparing a series of trichoderma C8 oxime ether derivatives. The trichomycin C8 oxime ether derivatives can be used as fungicides in agriculture and gardening to inhibit plant pathogenic fungi. |