http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103524403-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-30 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C55-10 |
filingDate | 2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103524403-B |
titleOfInvention | A kind of preparation method of doxylamine succinate |
abstract | The present invention relates to a kind of preparation method of doxylamine succinate, first the Grignard reagent of selecting iodobenzene and magnesium to generate reacts with 2-acetylpyridine and generates 2-pyridine radicals phenylmethylcarbinol, through recrystallization purifying, then 2-pyridine radicals phenylmethylcarbinol is successively with Sodamide and the reaction of 2-dimethylamino chloroethanes, obtain doxylamine, last doxylamine and butanedioic acid salt-forming reaction obtain doxylamine succinate. This preparation technology reaction efficiency is high, and cost is lower, is applicable to industrialized production. |
priorityDate | 2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 65.