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filingDate 2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-103524359-B
titleOfInvention A kind of with three big steric hindrance substituting group C2Symmetrical optically-active aminodiol and preparation method and purposes
abstract The present invention discloses a kind of with three big steric hindrance substituting group C 2 Symmetrical optically-active aminodiol and preparation method and purposes, the described C with three big steric hindrance substituting groups 2 Symmetrical optically-active aminodiol is chiral carbon be R configuration or chiral carbon is the structure of S configuration, it is possible to enantioselectivity induction metallic alkide organic compound is to the addition reaction of aldehyde radical; R in the achiral reagent used in process by being adjusted to 1 And R 2 Space steric hindrance size regulate addition reaction product e.e. value; At suitable R 1 And R 2 The e.e. value of addition reaction product of aldehyde radical of the lower enantioselectivity induction of combination up to more than 98%.
priorityDate 2013-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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