http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103520125-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 |
filingDate | 2013-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103520125-B |
titleOfInvention | A kind of telmisartan composition |
abstract | Technical Field: The present invention relates to a telmisartan pharmaceutical composition for treating hypertension, which belongs to the field of medical technology. The technical solution of the present invention is characterized in that the micronization technology is adopted: the mixture of the main drug, sodium hydroxide and mannitol is micronized by a jet mill, and the mixture of telmisartan, sodium hydroxide and mannitol after the micronization D90 is Between 3.0μm-5.0μm. The technical scheme of the invention simplifies the preparation method of telmisartan tablets, shortens the preparation period and material loss, and ensures that the tablet has a higher dissolution rate; secondly, through the use of micronization technology, the dissolution rate of the drug is improved , The particles prepared by micronization technology have good fluidity and compressibility, and do not need to use sorbitol with strong hygroscopicity, which improves the stability of the sample. |
priorityDate | 2013-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.