| abstract |
The invention provides coding based on the nucleic acid of support such as complete antibody, Fab fragments, single-chain antibody, soluble VEGF-receptor-Fc fusion rotein and/or the angiogenesis inhibitor pdgf receptor of antibody and peptide sequence.Also comprise the clone of coding this kind of angiogenesis inhibitor antibody scaffold, vegf receptor and/or pdgf receptor.The present invention also provides the encapsulation of cells therapy device that can send this kind of angiogenesis inhibitor antibody scaffold, vegf receptor and/or pdgf receptor and uses these devices to send angiogenesis inhibitor antibody scaffold, vegf receptor and/or pdgf receptor to cure the method for the illness of patient, and described illness comprises ophthalmic diseases, vascular disease, inflammatory diseases and cell breeding disease. |