http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103502462-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0063 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1081 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y301-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y204-99001 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-18 |
| filingDate | 2012-02-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103502462-B |
| titleOfInvention | Manufacture method containing sialic sugar chain |
| abstract | Known sialic acid is connected to the importance of the sugar chain of the non-reducing end of sugar chain with α 2,3 connections or α 2,6, there is the demand of the industrialized production to this sugar chain composition.Especially, when such as manufacturing glycoprotein, while controlling sialic connection mode (α 2,6 connects or α 2,3 connects), the sugar chain of large-scale production homogeneous structural is indispensable.N type complex-type sugar chain for 3 branching types or 4 branching types, it is considered that be difficult to chemosynthesis and be respectively provided with sialic sugar chain at all of non-reducing end, the most not yet reported this sugar chain of chemosynthesis.Also it is difficult in zymetology prepare this sugar chain efficiently.In the present invention, new discovery sialyltransferase has the sialic activity in the presence of CMP in cleavage reaction product, and discovery can decompose CMP by enzyme, thus manufactures efficiently containing sialic sugar chain.And then also find, for be difficult to traditionally to synthesize with α 2, the 64 branch's N type sugar chains connecting the acid of addition four molecular salivary, can be with 2 branching type sugar chains as raw material, carry out sugar chain and extend reaction, in the case of purification after not carrying out each step enzyme reaction, in one pot synthesis and high productivity is prepared. |
| priorityDate | 2011-03-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 243.