| abstract |
The present disclosure provides various compounds and pharmaceutically acceptable salts as inhibitors of tyrosine kinases, specifically BLK, BMX, EGFR, HER2, HER4, ITK, JAK3, TEC, Btk, and TXK and thus are useful for Inhibition of tyrosine kinases is useful in the treatment of diseases for which inhibition of tyrosine kinases is treatable (eg, cancer and inflammatory diseases (eg, arthritis), etc.). Also provided herein are pharmaceutical compositions comprising such compounds and pharmaceutically acceptable salts and methods for preparing such compounds and pharmaceutically acceptable salts. |