http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103497200-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-181 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
| filingDate | 2013-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-103497200-B |
| titleOfInvention | A kind of Dihydroartemisinin higher fatty acid ester and preparation method thereof |
| abstract | The invention discloses a kind of Dihydroartemisinin higher fatty acid ester and preparation method thereof. Mainly with lipase for catalyst, 10 carbon of dihydroartemisinine are carried out structural modification, make higher fatty acids and the hydroxyl generation esterification on 10 carbon of dihydroartemisinine. Specifically; with lipase Novozyme435 for catalyst; with stearic acid and lauric acid for acry radical donor; the tert-butyl alcohol is reaction dissolvent; 4A molecular sieve is the absorbent of water in esterification; it is amphipathic that the arteannuin esterification products prepared not only has profit, and Antimicrobial test shows good specific performance. The present invention, to improving arteannuin dissolubility in coil neutralization water, makes suitable dosage form and has great significance. |
| priorityDate | 2013-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 100.