| abstract |
The invention relates to the field of medicinal chemistry, in particular to a novel class of benzazepinone derivatives (I), a preparation method thereof and a medical application thereof. This kind of compound has the effect of inhibiting glycogen phosphorylase, and can be used to prepare anti-diabetes and its complications drugs, anti-cerebral ischemia drugs, anti-cardiovascular disease drugs, blood lipid-lowering drugs, weight-loss drugs, anti-atherosclerosis drugs, therapeutic Metabolic syndrome drugs or antineoplastic drugs. The invention also relates to processes for the preparation of these compounds and pharmaceutical formulations containing them. |