http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103494768-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N5-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 |
filingDate | 2013-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2015-08-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-103494768-B |
titleOfInvention | Ciclopirox olamine vaginal expansive suppository, preparation method and detection method thereof |
abstract | The invention relates to a ciclopirox olamine vaginal expansive suppository and a preparation method and a detection method thereof. The expansive suppository comprises a drug-containing matrix and an expansion carrier formed of ciclopirox olamine and a matrix; the organic acid in the drug-containing matrix and the Ciclopirox olamine has been made into a solid dispersion, and forms a double salt with ciclopirox olamine, which can promote the absorption of ciclopirox olamine, improve the bioavailability of the expansion plug, and maintain the acidic environment in the vagina; the hollow The effervescent expansive vaginal suppository overcomes the peak-valley phenomenon of drug release, further improves the stability of the expansive suppository, and the curative effect can reach the deep part of the vagina and folds; The release of piroxolamine is more conducive to the formation of suppositories; and the ciclopirox olamine vaginal expansion suppository provided by the present invention adopts six original leading technologies, which can prevent the outflow of medicinal liquid, have high stability, long-lasting curative effect, and prevent secondary Infection and other beneficial effects. |
priorityDate | 2013-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.